Dunfermline will be without on-loan St Johnstone defender Kevin Rutkiewicz after a training ground ankle knock.
He joins Andy Dowie and Steven Bell on the sidelines while the Pars will wait until the last minute for defender Neil McGregor to prove his fitness.
Queen of the South manager Kenny Brannigan:"We played really well down at Morton last weekend and David was clinical in his finishing and that was missed against Stirling Albion in midweek.
"If David makes it he'll be playing in his favoured position of through the middle and hopefully he'll grab some more goals in this game."
Dunfermline manager Jim McIntyre: "Both teams have creative players and goalscorers in their ranks, so it should be an exciting contest.
"We lost bad goals in the game there earlier in the season, so we want to put that right.
"As long as we score at least one more than them I will be happy."
Source: BBC Sport
Source: BBC Sport